Peanut allergy

In last couple of years there has been a huge surge in food allergy cases especially those involving peanuts. The cases literally doubled between 1997-2002 and its been on rise since.

incidence-of-peanut-allergies-in-us-population-1997-2010-percentage_chartbuilder

It accounts to 150 – 200 deaths every year and close to 9500 children are admitted to hospitals due to some form of food allergy.

The symptoms can show in matter of minutes to few hours. Some of common symptoms include hives, irritation on skin, running nose, swelling, blockage of throat, etc. It can even cause Anaphylaxis or cardiac arrest.

allergy_symptoms

Anaphylaxis symptoms include constriction of airway, swelling of throat, drop in blood pressure, rapid pulse, dizziness and loss of consciousness.

signs-and-symptoms-img

We have not yet figured why suddenly our body is rejecting food items like peanuts which we are so used to eating. Usually, the allergy tends to develop if children are not exposed to eating peanuts from a young age.

But why it has exploded in last few decades? The answer is embedded in the evolution of our micro-biome. In my previous article i had outlined how microbes can communicate to brain and rest of body from your gut. Similarly, if microbes wrongly identify peanut protein as harmful, it will send signal to the immune system to activate the defence system.

From biological standpoint, people with food allergy create a type of antibody called immunoglobulin E. These antibody bind to immune cells (mast cells & basophils) that circulate throughout the body. On exposure to the food allergen, it attaches to the immunoglobulin E antibodies. This binding signals the immune cells to release histamine and other chemicals to combat the compromise. The release causes the allergy symptoms which are visible like swelling, hives, etc mentioned above.

allergy-process

Immediate fix for Anaphylaxis reaction is the use of epinephrine hormone which maintains blood pressure and opens up the airways.

epinephrine

The drug can be administered using an auto injector. The video below demonstrates how to use an auto injector.

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